Conditions & Treatments
What we evaluate and how we treat it
The Neurogenesis Project is a direct-care neurology practice led by Sean C. Orr, M.D., a fellowship-trained neurologist, and Dr. Drew Edwards, our Chief Clinical Officer. Every treatment plan starts with a neurological evaluation, and the therapies below are used only when that evaluation supports them.
Medical care is delivered at our St. Marys, Georgia office; neurocoaching is also available in Jacksonville Beach, Florida. Not sure where you fit? Schedule an appointment and we will tell you whether we can help.
Conditions
Problems people bring to us, and what the evaluation looks for.
Memory Loss & Cognitive Decline
Imaging, biomarkers and neuropsychological testing to find why memory is slipping, then a plan built on those findings.
Alzheimer’s Prevention & Early Intervention
Blood biomarkers, APOE genotyping and metabolic work for people with a family history, mild cognitive impairment or early symptoms.
Traumatic Brain Injury & Concussion
Evaluation and treatment for lingering effects of concussion and TBI, including headaches, fog, sleep and mood changes.
Stroke Recovery
Neurological follow-up after stroke from a neurologist with fellowship training in vascular neurology.
Long COVID Clinic: Brain Fog
A neurological workup for persistent cognitive symptoms after COVID-19.
Chronic Fatigue Syndrome (ME/CFS)
Looking for neuroinflammatory and metabolic contributors to fatigue that standard labs miss.
MS & Neuroinflammation Treatment
Adjunctive care alongside, not instead of, disease-modifying therapy.
Headache & Migraine
Diagnosis and treatment of chronic headache, including procedural options.
Peripheral Neuropathy
Finding the cause of numbness, burning or weakness in the hands and feet.
Chronic Pain
A neurological approach to central sensitization, CRPS and post-concussive pain.
Brain Fog Treatment
Brain fog is a symptom with a cause. The evaluation looks for the metabolic, sleep, hormonal or inflammatory driver behind it.
Treatment-Resistant Depression
A neurological workup when antidepressants have not worked: imaging, inflammation, hormones, sleep and metabolic labs.
Anxiety: A Neurological Approach
Looking at the brain circuits, autonomic state and medical contributors behind anxiety that keeps coming back.
Executive Health Program
Baseline brain benchmarking and a plan for professionals who want to protect and sharpen performance.
Memory Loss Evaluation
A structured workup for new or worsening forgetfulness: history, exam, cognitive testing, labs and imaging.
Multiple Sclerosis
Neurological follow-up and adjunctive care for MS, coordinated with your MS specialist.
Normal Pressure Hydrocephalus
Evaluation for the treatable triad of gait change, memory loss and bladder urgency.
Hydrocephalus
Imaging review and neurological assessment of enlarged ventricles and CSF flow problems.
Dizziness & Vertigo
Sorting inner-ear, brain and blood-pressure causes of dizziness, with a plan for each.
Imbalance & Gait Disorders
Why walking has changed: neuropathy, vestibular, cerebellar and other neurological causes.
Numbness & Tingling
Finding where along the nerve pathway the problem starts, from the spine to the hands and feet.
Sports Concussion
Concussion evaluation and return-to-play or return-to-learn decisions based on objective testing.
Veterans’ Brain Health
Evaluation of blast exposure, TBI and overlapping PTSD symptoms, coordinated with VA care.
PTSD & the Brain
A neurological look at how trauma changes the brain, alongside your mental health providers.
Insomnia & Sleep Disorders
Neurological causes of poor sleep and how disrupted sleep affects memory and mood.
Sleep Apnea & the Brain
What untreated sleep apnea does to cognition, and how treating it protects the brain.
Persistent Fatigue
A neurological workup for fatigue that has outlasted rest and normal labs.
Fibromyalgia
Fibromyalgia as a disorder of central pain processing, with a treatment plan to match.
Burnout & Cognitive Recovery
Measuring what chronic stress has done to attention and memory, then rebuilding it.
Therapies & procedures
Treatments we offer. Most are delivered as part of the Intensive Brain Health Program after a full evaluation.
NAD+ IV Therapy
Intravenous NAD+ to support cellular energy metabolism.
Niagen IV Therapy (Nicotinamide Riboside)
The NAD+ precursor, infused in about an hour instead of the 2 to 4 hours NAD+ takes.
Myers’ Cocktail IV Therapy
Magnesium, B vitamins, calcium and vitamin C delivered intravenously.
Glutathione IV Therapy
Intravenous glutathione, the brain’s main endogenous antioxidant.
Stem Cell Therapy
Regenerative therapy offered at the St. Marys, GA office.
Exosome IV Therapy
Cell-derived signaling vesicles used in our regenerative protocols.
Chemodenervation for Chronic Migraine
Botulinum toxin injections following the PREEMPT protocol.
Occipital Nerve Block
An office procedure for occipital neuralgia and headache disorders.
NeuroCoaching
Brain-based coaching with Dr. Drew Edwards.
Trigger Point Injection
An office injection that releases a painful muscle knot in the neck, shoulders or back.
TMS (by Referral)
Evaluation by Dr. Orr and referral to a trusted local TMS center, with coordinated care.
Diagnostics
Testing that informs the plan. Every evaluation begins here.
Brain Health Lab Panels & Dementia Blood Test
Blood work for inflammation, metabolism, nutrients and neurodegeneration risk.
Advanced Brain MRI & Neuroimaging
Our NeuroCognitive MRI protocol surfaces findings that standard outpatient imaging misses.
MRI of the Brain & Spinal Cord
Structural imaging with advanced sequences — FLAIR, SWI, DTI and volumetrics — protocoled by a neurologist.
Brain MRA (MRI Angiography)
Non-invasive vascular imaging of the brain and neck arteries. No contrast required.
CSF Leak MRI (Cisternography)
Specialized CSF-space imaging for leak evaluation, hydrocephalus and Chiari assessment.
DTI Brain Scan (Diffusion Tensor Imaging)
White matter tractography that reveals injury conventional MRI calls normal.
NeuroQuant MRI
FDA-cleared automated brain volume measurement against age-matched norms.
Brain PET Scan for Dementia
FDG-PET maps glucose metabolism to show which brain regions are working and which are not.
Brain CT Scan Review
Ordering and expert review of brain CT when MRI is not possible, including outside scans.
Carotid & Transcranial Doppler Ultrasound
Non-invasive vascular ultrasound for stroke prevention, stenosis and cerebrovascular reserve.
EEG Test (Electroencephalogram)
Diagnostic EEG for seizures and unexplained spells, performed by a partner lab on Dr. Orr's referral.