The Neurogenesis Project
St. Marys, Georgia
Direct-care neurology and Cellular Rejuvenation Therapy on the Georgia coast, led by Dr. Sean C. Orr, MD — fellowship-trained neurologist and founder of The Neurogenesis Project.
Visit the office
The Neurogenesis Project — St. Marys
1191 Charlie Smith Sr. Hwy., Suite F
St. Marys, GA 31558
Finding the suite
We share the building with the Fairway Mortgage office, right next door to the Navy Federal Credit Union. Suite F is on the first floor — go through the door on the right side of the lobby.
Areas we serve
St. Marys, GA · Kingsland, GA · Brunswick, GA · Camden County · Fernandina Beach, FL · Amelia Island · Jacksonville, FL

Dr. Sean C. Orr, MD
Neurologist & Chief Medical Officer
Fellowship-Trained · Vascular, Critical Care & Interventional Neurology
Dr. Orr is the licensed neurologist of record at the St. Marys office. His clinical interest is the brain that conventional care has stopped working on: late-stage concussion, long-COVID neurology, early neurodegeneration, and addiction-related cognitive injury. Cellular Rejuvenation Therapy is the regenerative dimension of that practice.
Read Dr. Orr’s full bio →What we do at this office
The full clinical menu, with Cellular Rejuvenation as the dedicated St. Marys program
Cellular Rejuvenation Therapy
FeaturedBrain-directed cellular biologics for traumatic brain injury, post-COVID neurological symptoms, early-stage neurodegeneration, and substance-induced brain injury. The St. Marys office is the dedicated site for this program.
Read more →Intensive Brain Health Program
Multi-day immersive evaluation and treatment combining precision neuroimaging, neurogenomic and neurometabolic workup, and targeted therapeutic protocols. Designed for patients who want months of work compressed into days.
Read more →Rescue From Rehab
Brain-first approach to addiction recovery and post-acute withdrawal cognitive impairment. Combines neurological evaluation, regenerative protocols, and ongoing neurocoaching with Dr. Drew Edwards.
Read more →Neurological Services
Direct-access neurology consultations, in-office procedures (botulinum, occipital nerve blocks, trigger point injections), neuroimage review, and deep brain-health lab panels designed to surface what conventional bloodwork misses.
Read more →A destination office
St. Marys sits at the crossroads of the Georgia Golden Isles and the First Coast of Florida. Patients travel from Jacksonville, Brunswick, Fernandina Beach, and Amelia Island. For multi-day protocols, we suggest arriving the day before treatment begins and staying nearby; resort accommodations on Jekyll Island, Amelia Island, and in Kingsland are all within a short drive.
The clinic operates on a direct-care model. You contract directly with your physician. Insurance is not in the room.
Start with the consultation.
The first conversation is complimentary. If we are not the right answer for your case, we will say that plainly. If we are, the next step is the Diagnostic Process and a protocol designed around what we find.
Request a Discovery Consultation